(203) 208-3464 info@wrenlaboratories.com
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Our history

A decade of turning mRNA into medicine.

Wren’s scientific work on liquid biopsy began in 2004; the laboratory was established in Branford, Connecticut, in 2014.

2014Year Wren Laboratories was founded
115+Patents
30Genes analyzed by PROSTest® (27 + 3)
95%PROSTest® clinical accuracy (vs 48% for PSA)
Timeline

Milestones, newest first.

SEP2025
PROSTest®: large screening study (800 men) for prostate cancer
MAY2025
NETest 2.0® submitted to NYSDOH
APR2025
PROSTest® approved by NYSDOH.
FEB2025
ISO15189 certification submitted.
JAN2025
NETest 2.0® developed.
JUN2024
Finalizing two clinical studies evaluating the PROSTest® as a monitor for 177Lu-PSMA (Pluvicto) radioligand therapy (RLT).
MAY2024
PROSTest® approved by CLIA and submitted to NYSDOH.
MAR2024
Completed the evaluation of the PROSTest® as a marker for minimal residual disease (MRD).
OCT2023
Completed PROSTest® clinical validation study.
MAR2023
Development of the PROSTest® – a molecular genomic assay for prostate cancers.
DEC2022
CAP certification.
NOV2019
Set-up of NETesting at Sarah Cannon, UK.
OCT2018
Development of the PPQ – PRRT Predictive Quotient.
AUG2018
New York State Department of Health Permit – NETest.®
MAY2018
California Department of Health Permit – NETest.®
OCT2014
Clinical laboratory certification in Connecticut, CLIA license for the NETest.®
JUL2014
Laboratory establishment, Branford, Connecticut.
From history to innovation

Precision oncology through mRNA liquid biopsy.

The power of mRNA

Positioned between DNA and proteins, mRNA in whole blood gives a real-time picture of tumor activity. Our novel preservative ensures stable, reliable testing.

Our mission

Innovative machine learning, liquid biopsy-RNA in vitro diagnostics for detecting minimal residual disease and predicting cancer prognosis and response to therapeutics.

For decades, cancer management relied on imaging, invasive tissue biopsies and delayed recognition of residual or recurrent disease. Recognizing the need for more sensitive, dynamic molecular monitoring, Wren’s scientific efforts began exploring liquid biopsy technologies in 2004 to detect cancer-associated genetic activity through circulating biomarkers in blood and other non-invasive specimens.

Today, Wren focuses on advanced mRNA-based molecular diagnostics and machine-learning-enhanced bioinformatics supporting earlier cancer detection, molecular surveillance, treatment monitoring and precision oncology. By analyzing tumor-associated genetic signatures from blood and saliva, Wren aims to improve detection of minimal residual disease, recurrence risk assessment and real-time disease monitoring.

Wren’s growing portfolio targets prostate cancer, neuroendocrine tumors, colorectal, pancreatic and lung cancer, melanoma and hematologic malignancies. Through a simple blood or saliva sample, Wren is helping make mRNA liquid biopsy a practical clinical reality.

Get started

Providers, order your test here

Order NETest 2.0® or PROSTest® through our portal or with the requisition form — kits ship directly to your office.